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pentobarbital will reduce the extent or effect of elbasvir/grazoprevir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic influence of elbasvir/grazoprevir may be decreased if coadministered with solid CYP3A inducers and is particularly for that reason contraindicated.Opioid analgesics might be normal or arti